부산대학교 도서관

Five cases of septicemia were treated with mezlocillin.Two patients had subacute bacterial endocarditis (SBE) caused by α-Streptococcus, one case had SBE caused by Pasteurella gallinarum and the two remaining cases had typhoid fever. Streptococcal septicemias were completely cured with mezlocillin in doses of 12 g per day by drip infusion for 85 and 39 days respectively. The septicemia caused by P. gallinarum was medicated with a dose of 4 g per day, but treatment had to be stopped due to rashes appearing after 23 days.The patient had fever again 4 days after, and P. gallinarum was isolated again from her venous blood. No efficacy was found in the patients with typhoid feverResults of the sensitivity test with freshly isolated strains by using the disc method show that mezlocillin is effective against infections by gram positive microbes and gram negative bacilli such as Enterobacter, Haemophilus and Proteus species.