부산대학교 도서관

We report a case of cutaneous calcinosis following extravasation of calcium gluconate. A 3-year-old female was treated for a decreased serum calcium level with an intravenous injection of calcium gluconate. Six days later, erythema and swelling were observed at the injection site on her right arm. After 20 days, a yellowish-white subcutaneous nodule appeared at the site. An X-ray examination showed a subcutaneous high-density region. HE staining of a biopsy specimen showed the deposition of amorphous basophilic material at the dermal site. Von Kossa staining confirmed that this deposit to be calcium. Transepidermal elimination occurred in some nodules. All the deposits disappeared without treatment within 6 months.