학술논문
Study on the Quality of Polysorbate 80 Used for Dissolution Test of Spironolactone Tablets / スピロノラクトン錠の溶出試験に用いるポリソルベート80の品質に関する研究
Document Type
Journal Article
Author
Source
医薬品医療機器レギュラトリーサイエンス / Pharmaceutical and Medical Device Regulatory Science. 2023, 54(2):175
Subject
Language
Japanese
ISSN
1884-6076
2436-6226
2436-6226
Abstract
To use PS80 a test solution for dissolution test employing UV-visible spectrophotometry as the measurement method, it was necessary to confirm PS80 have no interference at the measurement wavelength. In case any interference are observed, it may be preferable to perform dissolution tests using HPLC as the detection method.