학술논문
New technology and Information Science for Next Generation Drug Modalities / 新技術と情報科学による新時代の創薬モダリティ
Document Type
Journal Article
Author
Source
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023, :1-SL05
Subject
Language
Japanese
ISSN
2435-4953
Abstract
Antibody as a drug modality contributes to the first runner of biomedicine. Recently, research and development of next generation antibody drugs has remarkable progresses on therapy, e.g. antibody drug conjugate (ADC), bispecific antibody (bsAb), and single domain antibody (VHH, also called nanobody), which has widen the application areas of antibody drugs. These include combination of elemental technologies, and incorporation of information sciences into the drug development. Here I would discuss next generation drug modality, especially focusing on innovation-driven antibody engineering.