학술논문
Specificity of intracytoplasmic inclusions appearing in uterine cervical cytology for chlamydia trachomatis genital infection ―Inspection based on the chlamydia trachomatis nucleic acid amplification test― / 子宮頸部細胞診に出現するクラミジア封入体細胞の特異性 ―クラミジア核酸増幅検査に基づく検証―
Document Type
Journal Article
Author
Source
日本臨床細胞学会雑誌 / The Journal of the Japanese Society of Clinical Cytology. 2022, 61(2):98
Subject
Language
Japanese
ISSN
0387-1193
1882-7233
1882-7233
Abstract
Study Design : We enrolled a total of 28 patients with CT infection (CT-infected group) and 30 patients without CT infection (non-CT-infected group) as confirmed by real-time PCR (qPCR). Three types of IIs were detected in the cervical cytology specimens : (1) nebular inclusion (N1), (2) intracytoplasmic inclusion (ICI), and (3) central target formation (CTF). To determine if any of the IIs were specific for genital CT infection, we performed immunocytochemistry with anti-CT antibody and calculated both the rates of detection of the IIs and the rate of immunopositivity (IMP) for CT antigen in the cervical cytology specimens of the study subjects.