부산대학교 도서관

An 82-year-old man who visited a neighboring hospital because of a mass lesion of the left breast was detected to have a 25-mm tumor right under the left nipple. He was referred to our hospital with a diagnosis of invasive ductal carcinoma following a fine needle biopsy. On physical examination, we palpated a tumor right under the left nipple which showed redness on the skin and fixation to the chest wall. Ultrasonography (US), mammography (MMG) and computed tomography (CT) revealed invasive ductal carcinoma of the left breast. The histological diagnosis was invasive ductal carcinoma (cT2N1M0, Stage IIB) and total mastectomy with axillary lymph node resection was performed. The final pathological diagnosis was invasive micropapillary carcinoma (IMPC) and multiple metastases of axillary lymph nodes [pT2, 23×22×17mm, f, s, HG II, NG II, 1y+, v-, pN3a (Level-I : 16/17, Level-II : 10/10) ER(+), PgR(+), HER2(-), MIB-1 : 9%]. After the surgery, he received radiation therapy to the chest wall and the supraclavicular fossa and endocrine therapy. He is alive without recurrence as of 16 months after the operation. Since invasive micropapillary carcinoma rarely arises in the male breast, we present our case together with a review of the literature.