학술논문

Transjugular intrahepatic portosystemic shunt for the treatment of refractory hepatic hydrothorax / 経頸静脈的肝内門脈大循環短絡術(TIPS)による難治性肝性胸水の治療
Document Type
Journal Article
Source
肝臓 / Kanzo. 2020, 61(8):399
Subject
TIPS
cirrhosis
portal hypertension
refractory ascites
refractory hepatic hydrothorax
transjugular intrahepatic portosystemic shunt (TIPS)
肝硬変
門脈圧亢進症
難治性肝性胸水
難治性腹水
Language
Japanese
ISSN
0451-4203
1881-3593
Abstract
Patients with refractory hepatic hydrothorax (HHT) who fail to respond to medical treatment experience a low quality of life and poor prognosis. In this study, we evaluated the use of transjugular intrahepatic portosystemic shunt (TIPS) in 20 patients with refractory HHT from 2001 to 2015. The mean age was 61.1±10.8 years and the mean Child-Pugh score (CPS) was 9.7±1.5 points. All patients experienced successful insertion of the TIPS and had no need for thoracenteses after TIPS. The one-year survival rate among all patients was 69% and the median survival length was 23.2 months; otherwise, the results were improved to 73% and 27.8 months when the analysis was limited to patients with a CPS score of less than 11 points. Two of four patients with CPS scores of 12 points died of liver failure within 60 days after TIPS. In conclusion, TIPS is effective for refractory HHT and may improve the survival of patients; however, its use should be limited to patients with CPS scores of less than 11 points.