학술논문

Significance and Problems of Hepatic Resection for Hepatocellular Carcinoma and Borderline Lesions in Terms of Recurrence in the Remnant Liver / 残肝再発からみた肝細胞癌および併存する境界病変合併切除の意義と問題点
Document Type
Journal Article
Source
日本消化器外科学会雑誌 / The Japanese Journal of Gastroenterological Surgery. 1995, 28(11):2168
Subject
borderline lesions
computed tomography during hepatic arteriography and arterioportography
early hepatocellular carcinoma
hepatocellular carcinoma
liver cirrhosis
Language
Japanese
ISSN
0386-9768
1348-9372
Abstract
This study was carried out to evaluate the significance and problems of hepatic resection for borderline lesions, concomitant with hepatocellular carcinoma (HCC) which were detected by computed tomography during angiography (angio CT), in terms of recurrences within one year of the resection. There were 39 lesions in 20 patients. Eleven of the 20 patients (55%) had multiple lesions including early HCC and borderline lesions that suggested multicentric occurrence. Recurrences in the remnant liver were found in four out of twenty patients (20%) within a year of hepatic resection. There were more recurrences in the remnant liver in patients with multiple lesions than in those with a single lesion. In patients with multiple lesions who underwent relative noncurative resection or operative ethanol injection therapy because lesions occupied bilateral lobes, there were more recurrences in the remnant liver. Recurrences in the remnant liver occurred in patients with liver cirrhosis more than in patients with chronic hepatitis. There were many recurrences with multiple lesions. The detection by angio CT of multiple lesions and the resection of as many lesions as possible, contributd to the decrease in the number of recurrences within a year of hepatic resection. However, why there were many multiple recurrences that were impossible to re-operate on after hepatic resection is a question which still remains to be studied.