학술논문

A Case of a Perforated Appendiceal Diverticulum Complicated by an Appendiceal Goblet Cell Carcinoid Lesion / 虫垂杯細胞カルチノイドを合併した虫垂憩室穿孔の1例
Document Type
Journal Article
Source
日本臨床外科学会雑誌 / Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 2013, 74(6):1596
Subject
appendiceal goblet cell carcinoid
perforated appendiceal diverciculum
虫垂憩室穿孔
虫垂杯細胞カルチノイド
Language
Japanese
ISSN
1345-2843
1882-5133
Abstract
Both an appendiceal diverticulum and an appendiceal goblet cell carcinoid lesion are rare. In this report, a case in which these conditions occurred concurrently is presented along with a review of the literature. A 70-year-old woman had right lower abdominal pain. Abscess formation due to appendiceal perforation was diagnosed. An emergency appendectomy and drainage were performed. On histopathology, evidence of a goblet cell carcinoid lesion was found on the proximal side, and perforation of one of the multiple pseudo-diverticula was noted on the distal side of the appendix. The lesions were far apart and were judged to have occurred independently. Since the surgical margin was negative, neither additional surgeryn or postoperative adjuvant chemotherapy was required. An appendiceal goblet cell carcinoid lesion is a variation of a carcinoid tumor, but it is considered to have a high malignant potential which results in a poor prognosis. Only 105 cases of appendiceal goblet cell carcinoid lesions including our case have been reported in Japan. No consensus has been reached regarding the optimal treatment or prognosis. Since the disease cannot be diagnosed unless the whole resected lesion is examined, many latent cases are considered to exist. Careful histological examination is necessary to make the diagnosis. Follow-up examinations are also considered to be important.