학술논문

A study on false positive results of hepatitis B surface antigen (HBsAg) test: Frequency of samples considered false positives in relation to the HBsAg concentration / HBs抗原検査の偽陽性に関する検討―濃度別にみた判定困難例の頻度
Document Type
Journal Article
Source
肝臓 / Kanzo. 2018, 59(11):641
Subject
B型肝炎ウイルス
HBc抗体
HBsAg
HBs抗原
anti-HBc
chemiluminescent enzyme immunoassay (CLIA)
false positive
hepatitis B virus
偽陽性
化学発光免疫測定法(CLIA)
Language
Japanese
ISSN
0451-4203
1881-3593
Abstract
The aim of this study was to clarify the percentage of samples considered false positive for hepatitis B surface antigen (HBsAg) in relation to the HBsAg concentration. The HBsAg concentrations were measured in 41,186 samples using chemiluminescent enzyme immunoassay. Samples with a concentration of ≥0.05 IU/mL were considered positive. The criteria for classifying a result as false positive were as follows: negative for anti-HBc, HBeAg, anti-HBe, and HBV-DNA as well as negative for HBsAg examined with the sample obtained on other day.