학술논문
A case of early gastric mixed neuroendocrine-non-neuroendocrine neoplasm resected by endoscopic submucosal dissection / 内視鏡的粘膜下層剥離術にて切除し得た早期胃MiNENの1例
Document Type
Journal Article
Author
Akira Madarame; Fumito Yamanishi; Hayato Yamaguchi; Kenichi Tadokoro; Kumiko Uchida; Masakatsu Fukuzawa; Ryoya Kanda; Sakiko Naito; Shin Kono; Sho Matsumoto; Taisuke Matsumoto; Takao Itoi; Takashi Kawai; Takashi Morise; Yohei Koyama; Yuji Mugishima; 内田 久美子; 内藤 咲貴子; 小山 洋平; 山口 隼; 山西 文門; 松本 将; 松本 泰輔; 森瀬 貴之; 河合 隆; 河野 真; 班目 明; 田所 健一; 神田 遼弥; 福澤 誠克; 糸井 隆夫; 麦島 悠司
Source
Progress of Digestive Endoscopy. 2023, 102(1):80
Subject
Language
Japanese
ISSN
1348-9844
2187-4999
2187-4999
Abstract
An 80-year-old man with a chief complaint of anemia underwent upper gastrointestinal endoscopy, and a 25-mm, white-toned, and elevated lesion was found on the posterior wall of the lower gastric body. Histopathological analysis revealed that the lesion was a mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) comprising adenocarcinoma and neuroendocrine tumor. This patient had an intramucosal carcinoma with a G1-equivalent neuroendocrine neoplasm (NEN) component, and no apparent recurrence 6 months after endoscopic submucosal dissection (ESD) resection. MiNEN is a relatively new concept, which was modified in the 2019 World Health Organization (WHO) classification, and there is currently a lack of an established treatment and evidence for this disease. Reports of endoscopic resection of early gastric MiNEN are rare. We here report a case of successful endoscopic resection in a patient with MiNEN, together with a literature review.