학술논문

Effect of Administration of Vitamin and Methionine on the Dark Adaptation, Urinary Sulfate and Creatinine in Adults and Children / 児童および成人の暗調応, 尿中硫酸, クレアチニンに及ぼすビタミンおよびメチオニン服用の影響
Document Type
Journal Article
Source
栄養と食糧 / Eiyo To Shokuryo. 1974, 27(5):211
Subject
Language
Japanese
ISSN
0021-5376
1883-8863
Abstract
1. The threshold value of perception of dark adaptation in school children, college women and residents in rice field area was improved significantly when they were dosed with a mixture of vitamin (thiamine, riboflavin, B6, pantothenic acid, nicotinic acid, ascorbic acid and vitamin A) and the value remainefd subnormal when the dose was lacking in thiamine, riboflavin, ascorbic acid, vitamin A or pantothenic acid.2. The threshold value in some of them became normal when the mixture of vitamin was given together with milk or methionine. The fact shows that their diet is in shortage of animal protein.3. After dosing methionine and watersoluble vitamin to junior college women there was a significant improvement of dark adaptation but the threshold value did not return to normal until vitamin A was supplemented. The addition of methionine increased the excretion of creatinine in almost all college women as well as in the aforementioned residents in rice field area. The results of urinary analyses indicate that addition of vitamin A together with watersoluble vitamin and methionine resulted in a marked increase of urinary ethereal sulfate.4. It was suggested that the degree of improvement in dark adaptation after the supplementation with vitamin A to a subject who has received adequate watersoluble vitamin and methionine would represent a measure of relative saturation of the body store as to vitamin A. And if his ethereal sulfate percentage in total sulfate does not reach 25% he might be diagnosed to be deficient in vitamin A.