학술논문

Myelodysplastic syndrome with refractory hemorrhage due to reduced platelet aggregation activity / 血小板凝集能低下により止血が困難であった骨髄異形成症候群
Document Type
Journal Article
Source
臨床血液 / Rinsho Ketsueki. 2017, 58(12):2402
Subject
Major bleeding
Myelodysplastic syndrome
Platelet dysfunction
Language
Japanese
ISSN
0485-1439
1882-0824
Abstract
A 75-year-old woman suffered a cat bite 10 months after myelodysplastic syndrome (MDS) diagnosis. She visited our hospital because the internal bleeding of the wound did not improve. Although the wound was treated, the bleeding did not stop. She was hospitalized for emergency medical treatment because the bleeding volume exceeded 200 ml. Although her platelet count was normal, the platelet function test showed a decrease in collagen and arachidonic acid aggregation. After platelet transfusion, her bleeding stopped. Patients with MDS may potentially have platelet dysfunction. In the case of bleeding without thrombocytopenia, a platelet function test should be performed and treatment intervention, such as platelet transfusion, should be considered.

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