학술논문

A Case of Mediastinal Tuberculous Lymphadenitis in a Peritoneal Dialysis Patient Diagnosed by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration / 腹膜透析患者に発症しEBUS-TBNAで診断し得た縦隔リンパ節結核の1例
Document Type
Journal Article
Source
気管支学 / The Journal of the Japan Society for Respiratory Endoscopy. 2020, 42(5):430
Subject
EBUS-TBNA
Mediastinal tuberculous lymphadenitis
Peritoneal dialysis
縦隔リンパ節結核
腹膜透析
Language
Japanese
ISSN
0287-2137
2186-0149
Abstract
Background. Extrapulmonary tuberculosis can be complicated in dialysis patients. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been considered useful for the diagnosis of mediastinal tuberculous lymphadenitis. However, there are few reports on patients receiving peritoneal dialysis, not blood dialysis. Case. An 89-year-old woman developed a persistent fever of around 38°C at 4 months after the initiation of peritoneal dialysis for end-stage kidney disease. Chest contrast-enhanced computed tomography (CT) showed multiple mediastinal lymphadenopathies without pulmonary lesions. We performed EBUS-TBNA on the subcarinal lymph node (#7) and collected samples, including pus. The histopathological result was epithelioid cell-like clusters of histiocytes, and Mycobacterium tuberculosis was identified in the specimen. We made a diagnosis of mediastinal tuberculous lymphadenitis and started her on treatment with isoniazid (INH), rifampicin (RFP), and ethambutol (EB). Her symptoms and mediastinal lymphadenopathy gradually improved after the treatment. Conclusion. In patients on dialysis with lymphadenopathy, we should consider the possibility of tuberculous lymphadenitis in addition to malignancies. EBUS-TBNA is highly effective for diagnosing mediastinal tuberculous lymphadenitis.