부산대학교 도서관

Hydrophilic polysulfone membrane (SPE-PSf) were prepared from PSf membranes covalently conjugated with a polymer of sulfoalkylbetaine (SPE) on the surface. The SPE-PSf membranes were found to be the most hydrophilic membranes among the PSf and surface-modified PSf membranes prepared in this study. This is explained by the long hydrophilic side chain of SPE on the SPE-PSf membranes, which contributes to the hydrophilic wiper on the hydrophobic PSf membranes. It was found that SPE-PSf membranes showed lower protein adsorption from a plasma solution than PSf and other surface-modified membranes. This is attributed to the hydrophilic surface of the SPE-PSf membranes, because a hydrophilic surface is known to reduce protein adsorption on the membranes. The SPE-PSf membranes showed a much-suppressed number of adhering platelets on the surface than PSf and other surface-modified membranes. It is suggested that the hydrophilic surface of the SPE-PSf membranes causes the suppression of platelets adhesion on the SPE-PSf membranes and that the long hydrophilic side chain of SPE on SPE-PSf membranes contributes to the hydrophilic and hemocompatible wipers on the surface of the hydrophilic PSf membranes.