학술논문
Rapid and nondestructive tissue clearing system（RAP）を用いた免疫組織化学的解析法の検討 / Tissue clearing by RAP system is available for immunohistochemistry
Document Type
Journal Article
Author
Source
Annual Meeting of the Japanese Society of Toxicology. 2020, :P-138
Subject
Language
Japanese
Abstract
We previously reported a rapid bone staining procedure (RAP-B) based on a rapid and nondestructive tissue clearing system (RAP system), preserving the histological structure of tissues even after the specimens were highly cleared. In the present study, we applied the RAP system to immunohistochemical observation. The RAP system improved permeation of antibodies into whole-mount specimens and thick tissue sections. Thus, we concluded that tissue clearing by RAP system could provide the great advance in immunohistochemical analysis.