부산대학교 도서관

Cefotiam (SCE-963) was given to 19 patients with urinary tract infections and 1 patient with bronchopneumonia in daily doses of 0.5-2g for 5-14 days. Responses were good in 13 patients, fair in 1 and poor in 6. Eight patients out of 11 with chronic urinary tract infections showed satisfactory citnical responses.Seven strains out of 10 isolates of E. coli, 2 out of 3 Streptococcus faecalis, 1 out of 2 Proteus mirabilis, 1 out of 2 Klebsiella and 1 isolates of Enterobacter were eradicated by cefotiam therapy.As side effects, exanthem was observed in 2 patients and transient elevation of GPT and blood platelets was noted.