학술논문

Clinical results of salvage surgery in hypopharynx carcinoma after chemoradiotherapy / 下咽頭癌における化学放射線療法後の救済手術合併症
Document Type
Journal Article
Source
頭頸部癌 / Toukeibu Gan. 2008, 34(4):488
Subject
Chemoradiotherapy
Hypopharynx carcinoma
Surgical complication
Survival rate
下咽頭癌
化学放射線療法
手術合併症
生存率
Language
Japanese
ISSN
1349-5747
1881-8382
Abstract
The incidence of post-operative complications and treatment results of 60 cases of hypopharynx carcinoma receiving laryngo-pharyngo-esophagectomy followed by reconstruction with jejunum after chemoradiotherapy (CRT) from 1997 to 2006 in 6 hospitals was analyzed. The overall complication rate was 57%. There were 3 cases with carotid artery rupture (5%), 4 with jejunum necrosis (6%), 6 with major salivary fistula (10%), 8 with minor salivary fistula (13%), 8 with abscess alone (13%), 3 with trachea stoma necrosis (5%), and 3 with skin flap necrosis (5%). The death rate due to surgical complications was 3% (2/60). When the cases were divided into two groups, namely the cases with fistula and the cases without fistula, the number of days that permitted drinking was 18.1 in the latter and 81.8 in the former. The 5-year overall survival rate among all cases was 37%. We found that salvage surgery after CRT was effective for recurrent cases. These findings suggest that reconstruction with jejunum is a suitable type of operation with better surgical results. Care is required to reduce the incidence of post-operative complications.