부산대학교 도서관

We encountered two cases of so-called postoperative erythroderma following open heart surgery. A 61-year-old female and a 60-year-old male developed fever, erythroderma, liver dysfunction, and pancytopenia about 10 days after coronary artery bypass grafting and subsequently died.Skin biopsy disclosed infiltration of lymphocytes in the basal epidermal layer, and immunohistological examination showed that most of these infiltrating cells were T cells. Although the chimerism of the patient's lymphocytes could not be identified, the typical clinical course and pathological findings of the skin biopsy coincided with previous reports of GVHD following blood transfusion. This disease is a fatal complication of transfusion. Therefore, we are attempting to prevent GVHD by avoiding the use of fresh blood, and decreasing the amount of transfusion by autotransfusion, same-day transfusion of the patient's own fresh blood, and the recycling of drained blood.