부산대학교 도서관

We investigated the relationship between the various values and free carnitine concentration in 258 hemodialysis patients. To investigate the association of laboratory values and free carnitine concentration of 125 healthy subjects, we compared the values of hemodialysis patients and healthy subjects. We divided 190 hemodialysis patients into four groups and conducted a prospective study to compare in various values to investigate the effects of carnitine IV with that of nutritional guidance. Free carnitine concentration and age of dialysis patients showed a negative correlation. Prealbumin and free carnitine concentration, muscle mass/height2 showed a significant positive correlation. Unlike dialysis patients, free carnitine concentration showed a positive correlation with age in healthy subjects. Carnitine by intravenous injection showed a marked increase of free carnitine concentration in hemodialysis patients. Free carnitine concentrations also increased in nutritional guidance group. Erythropoietin resistance index and lower limb entanglement was also investigated, those suggest that there is a limit to the effect of carnitine replacement therapy, it was considered that it is necessary to select patients in their use.