학술논문

Multiple sclerosis and neuromyelitis optica ; key points for differential diagnosis / 多発性硬化症と視神経脊髄炎;鑑別診断のポイント
Document Type
Journal Article
Source
神経治療学 / Neurological Therapeutics. 2022, 39(3):192
Subject
demyelinating diseases
differential diagnosis
multiple sclerosis
myelin oligodendrocyte glycoprotein
neuromyelitis optica
Language
Japanese
ISSN
0916-8443
2189-7824
Abstract
Central nervous system demyelinating diseases include multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), MOG–IgG related disorders (MOGAD). The diagnosis of MS is based on the exclusion of other diseases and the findings of MRI and cerebrospinal fluid examination. The diagnosis of NMOSD and MOGAD requires the identification of anti–aquaporin 4 antibodies and anti–myelin oligodendrocyte glycoprotein antibodies, respectively, using a cell–based assay. In addition, it is important to know the characteristic clinical and imaging features of each disease.