학술논문

A Case of Pathological CR after Imatinib Mesylate Therapy in a Rectal GIST / 術前Imatinib投与後に切除し,pCRであった直腸GISTの1例
Document Type
Journal Article
Source
日本大腸肛門病学会雑誌 / Nippon Daicho Komonbyo Gakkai Zasshi. 2017, 70(7):457
Subject
Neoadjuvant imatinib
pCR
rectal GIST
直腸GIST
術前Imatinib
Language
Japanese
ISSN
0047-1801
1882-9619
Abstract
We report a case of pathological CR after Imatinib mesylate therapy in a rectal GIST. A patient was a 76-year-old man who underwent lung cancer surgery. Follow-up PET-CT for the lung cancer showed FDG uptake in the rectum. FNA revealed rectal GIST. The tumor existed on the anterior wall of the Rb rectum, and widely bordered on the prostate gland, so we performed Imatinib mesylate therapy for the neoadjuvant chemotherapy. The tumor shrank from 28mm to 11mm in diameter, so we performed surgery. Pathological findings showed complete response for the chemotherapy. During 84 months of monitoring, there is no evidence of recurrence.