학술논문

Long-term efficacy of oral immunotherapy for hen's egg, cow's milk, and wheat allergies in children / 鶏卵,牛乳,小麦アレルギー児における経口免疫療法の長期的な有効性に関する検討
Document Type
Journal Article
Source
日本小児アレルギー学会誌 / Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology. 2020, 34(1):158
Subject
desensitization
food allergy
oral immunotherapy
経口免疫療法
脱感作
食物アレルギー
Language
Japanese
ISSN
0914-2649
1882-2738
Abstract
Results: A total of 77 participants (52%) responded to the survey; of these, 32 were allergic to hen's egg, 28 to cow's milk, and 17 to wheat. The survey was conducted over a median period of 6.4 years after the participants achieved the maintenance OIT dose. Moreover, the continuation rate of the maintenance OIT dose was 90%, without differences in terms of the offending food. Overall, 34 participants (44%) experienced allergic symptoms after the third year of the maintenance phase, without differences in terms of the offending food. The rate of severe symptoms was 5%, without differences in terms of the offending food, which necessitated the use of an adrenaline auto-injector, as recommended by the Japanese Society of Pediatric Allergy and Clinical Immunology.

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