학술논문

Anti-obesity Effects of Extracts from Irvingia gabonensis on High Fat Diet-induced Obese Mice / 高脂肪食負荷マウスにおけるアフリカマンゴノキ抽出物の 抗肥満作用
Document Type
Journal Article
Source
日本補完代替医療学会誌 / Japanese Journal of Complementary and Alternative Medicine. 2022, 19(1):47
Subject
Irvingia gabonensis
anti-obesity
ellagic acid
high-fat diet
mice
エラグ酸
マウス
抗肥満作用
高脂肪食
Language
Japanese
ISSN
1348-7922
1348-7930
Abstract
Irvingia gabonensis seed extract is known to have an anti-obesity effect. In this study, we confirmed this effect in high-fat diet-fed mice using the commercially available “Africamangonoki” food product with functional claims. As a result, significant reductions in body weight and visceral fat (excluding paratesticular fat) were observed in the high-fat food intake group containing the commercially available “Africamangonoki” product, compared with the high-fat food only intake group. Therefore, it was considered that the seed extract of Irvingia gabonensis has an excellent anti-obesity effect. Conversely, no anti-obesity effect was observed with ellagic acid, which is a component involved, suggesting that components other than ellagic acid may also be involved in the anti-obesity effect observed in relation to Irvingia gabonensis.