학술논문

The Effect of Assessment Method and Respondent Population on Utilities Elicited for Gaucher Disease
Document Type
research-article
Source
Quality of Life Research, 1997 Mar 01. 6(2), 169-184.
Subject
Gaucher disease
Multimedia
Patient preferences
Risk-risk trade-off
Standard gamble
Time trade-off
Gaucher disease
Chronic diseases
Quality of life
Bones
Pain
Spleen
Physicians
Multimedia materials
Research methods
Gold standard
Language
English
ISSN
09629343
15732649
Abstract
Measured preferences have been reported to vary with the method of elicitation and respondent population surveyed. We elicited utilities for Gaucher disease using a multimedia implementation of the time trade-off, standard gamble, and a conceptually different, largely untested approach, the risk-risk trade-off, from those who are healthy, those with a chronic illness and those with Gaucher disease. The risk-risk trade-off produced significantly lower utilities than the other two preference assessment methods and had the poorest test-retest reliability. The respondent's self-rated current health state utility was the most important determinant of utility values elicited by the time trade-off and standard gamble for the hypothetical health states. Our results do not support the use of our implementation of the risk-risk trade-off method. In eliciting preferences for hypothetical health states from the general population, the subjective rating of a respondent's own health state should be considered in determining representative population groups.