학술논문

Strength of association between umbilical cord pH and perinatal and long term outcomes: systematic review and meta-analysis
Document Type
research-article
Source
BMJ: British Medical Journal, 2010 May . 340(7756), 1121-1121.
Subject
Morbidity
Obstetrics
Neonatal mortality
Cerebral palsy
pH
Umbilical cord
Pregnancy outcome
Scholarly publishing
Brain hypoxia
Encephalopathies
Language
English
ISSN
09598138
17561833
Abstract
STUDY-QUESTION Is there an association between the pH of umbilical cord blood at birth and perinatal and long term outcomes? SUMMARY ANSWER Low arterial cord pH showed strong, consistent, and temporal associations with clinically important outcomes, including neonatal mortality, hypoxic ischaemic encephalopathy, seizures, intraventricular haemorrhage, and cerebral palsy. WHAT IS KNOWN AND WHAT THIS PAPER ADDS Neonatal and childhood mortality and morbidity, including cerebral palsy, are attributed to fetal acidosis, as defined by low cord pH at birth. Existing reports of the link between cord pH and adverse outcomes are conflicting. Our review found that low cord pH is substantially associated with neonatal mortality and morbidity, and cerebral palsy.