학술논문
The protein-free IANUS peptide array uncovers interaction sites between Escherichia coli parvulin 10 and alkyl hydroperoxide reductase
Document Type
Report
Author
Source
Biochemistry. Oct 5, 2010, Vol. 49 Issue 39, 8626-8635
Subject
Language
English
ISSN
0006-2960
Abstract
Parvulin 10 (Par10), an abundant Escherichia coli peptidyl prolyl cis/trans isomerase (PPlase), has physically interacted with the alkyl hydroperoxide reductase subunit C (AhpC) in bacterial cell extracts, which is determined by affinity chromatography and chemical cross-linking experiments. The studies have shown that Par10 catalytic activity is involved in the cellular protection against oxidative stress.