학술논문
Ultrasound-enhanced attenuated total reflection mid-infrared spectroscopy in-line probe: acquisition of cell spectra in a bioreactor
Document Type
Report
Author
Source
Analytical Chemistry. Feb 17, 2015, Vol. 87 Issue 4, p2314, 7 p.
Subject
Language
English
ISSN
0003-2700
Abstract
The article introduces a new method developed for selective acquisition of Fourier transform infrared (FT-IR) spectra of microorganisms in-line during fermentation, using Saccharomyces cerevisiae as a model. The findings are discussed in detail. It is concluded that ultrasound-enhanced in-line ATR mid-IR spectroscopy can be used as a real-time PAT method for the in situ monitoring of cellular biochemistry during fermentation.