학술논문
Adverse events associated with testosterone administration
Document Type
Clinical report
Author
Basaria, Shehzad; Coviello, Andrea D.; Travison, Thomas G.; Storer, Thomas W.; Farwell, Wildon R.; Jette, Alan M.; Eder, Richard; Tennstedt, Sharon; Ulloor, Jagadish; Anqi Zhang; Choong, Karen; Lakshman, Kishore M.; Mazer, Norman A.; Miciek, Renne; Krasnoff, Joanne; Elmi, Ayan; Knapp, Philip E.; Brooks, Brad; Appleman, Erica; Aggarwal, Sheetal; Bhasin, Geeta; Hede-Brierley, Leif; Bhatia, Ashmeet; LeBrasseur, Nathan; Fiore, Louis D.; Bhasin, Shalender; Collins, Lauren
Source
The New England Journal of Medicine. July 8, 2010, Vol. 363 Issue 2, p109, 14 p.
Subject
Language
English
ISSN
0028-4793
Abstract
A study was conducted to examine the safety and efficacy of testosterone treatment in older men who have limitations in mobility and also determine if testosterone supplementation increased muscle mass and strength in healthy older men. The application of a testosterone gel was observed to be associated with an increased risk of cardiovascular adverse events in population of older men with limitations in mobility and a high prevalence of chronic disease.