학술논문

Good laboratory practices guarantee biosafety in the Sierra Leone-China friendship biosafety laboratory
Document Type
Report
Source
Infectious Diseases of Poverty. June 23, 2016, Vol. 5 Issue 1
Subject
Biosafety -- Methods -- Safety and security measures
Best practices -- Evaluation -- Safety and security measures -- Methods
Laboratories -- Safety and security measures -- Methods
Ebola virus -- Safety and security measures -- Methods
Language
English
ISSN
2049-9957
Abstract
Background The outbreak of Ebola virus disease (EVD) in West Africa between 2014 and 2015 was the largest EDV epidemic since the identification of Ebola virus (EBOV) in 1976, and the countries most strongly affected were Sierra Leone, Guinea, and Liberia. Findings The Sierra Leone-China Friendship Biological Safety Laboratory (SLE-CHN Biosafety Lab), a fixed Biosafety Level 3 laboratory in the capital city of Sierra Leone, was established by the Chinese government and has been active in EBOV detection since 11 March 2015. Complete management and program documents were created for the SLE-CHN Biosafety Lab, and it was divided into four zones (the green, yellow, brown, and red zones) based on the risk assessment. Different types of safe and appropriate personnel protection equipment (PPE) are used in different zones of the laboratory, and it fully meets the Biosafety Level 3 laboratory standards of the World Health Organization. Conclusion Good preparedness, comprehensive risk assessment and operation documents, appropriate PPE, effective monitoring and intensive training, together with well-designed and reasonable laboratory sectioning are essential for guaranteeing biosafety. Keywords: Ebola virus, Ebola virus disease, Biosafety, SLE-CHN Biosafety Lab, BSL-3 laboratory
Author(s): Qin Wang[sup.1,2,3] , Wei-Min Zhou[sup.1,3] , Yong Zhang[sup.1,2,3] , Huan-Yu Wang[sup.1,2,4] , Hai-Jun Du[sup.1,2,4] , Kai Nie[sup.1,2,3] , Jing-Dong Song[sup.1,2,4] , Kang Xiao[sup.1,2,4] , Wen-Wen Lei[sup.1,2,4] , Jian-Qiang Guo[sup.1,2,3] [...]