학술논문
An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China
Document Type
Report
Source
International Journal of Antimicrobial Agents. Jan, 2008, Vol. 31 Issue 1, p50, 5 p.
Subject
Language
English
ISSN
0924-8579
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ijantimicag.2007.08.019 Byline: Zhiyong Zong (a)(b), Xiaoju Lu (a), Jubelle K. Valenzuela (b), Sally R. Partridge (b), Jon Iredell (b) Keywords: Oxacillinase; Carbapenemase; Acinetobacter baumannii; Integron; Acinetobacter-derived cephalosporinase Abstract: Twenty-two non-repetitive carbapenem-resistant Acinetobacter baumannii isolates were obtained from Intensive Care Unit patients. All of the isolates carried bla.sub.OXA-23, bla.sub.OXA-66, a novel cephalosporinase-encoding gene (bla.sub.ADC-25) and a class 1 integron with an aacC1-orfP-orfQ-aadA1a cassette array and had identical enterobacterial repetitive intergenic consensus (ERIC) profiles. ISAba1 was found upstream of bla.sub.OXA-23, but was not associated with bla.sub.OXA-66 or bla.sub.ADC-25. Author Affiliation: (a) Department of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China (b) Centre for Infectious Diseases and Microbiology, University of Sydney, Level 3 ICPMR Building, Westmead Hospital, Sydney, NSW 2145, Australia Article History: Received 17 June 2007; Accepted 28 August 2007