학술논문

Respiratory arrest precipitated by codeine in a child with chronic renal failure
Document Type
Periodical
Source
Clinical Pediatrics. March 1997, Vol. 36 Issue 3, p171, 3 p.
Subject
Causes of
Complications and side effects
Pediatric respiratory diseases -- Causes of
Respiratory insufficiency -- Causes of
Codeine -- Adverse and side effects
Chronic kidney failure -- Complications
Respiratory insufficiency in children -- Causes of
Language
ISSN
0009-9228
Abstract
Physicians should be especially careful when giving painkillers that contain codeine to children with a history of kidney failure. A 5-year-old boy with a history of kidney failure received a painkiller containing acetaminophen and codeine every 4 hours after he had his tonsils and adenoids removed. By the next morning, his parents found him blue and not breathing. He was rushed to a hospital where he was placed on a ventilator. Analysis of blood samples revealed that he had excessive levels of a metabolite of codeine because his kidneys could not eliminate it fast enough.