학술논문
Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults
Document Type
Clinical report
Author
Chen, Yiping; Kartsonaki, Christiana; Clarke, Robert; Guo, Yu; Du, Huaidong; Yu, Canqing; Yang, Ling; Pei, Pei; Stevens, Rebecca; Burgess, Sushila; Hua, Yujie; Chen, Junshi; Lv, Jun; Li, Liming; Chen, Zhengming; Collins, Rory; Peto, Richard; Walters, Robin; Avery, Daniel; Boxall, Ruth; Bennett, Derrick; Chang, Yumei; Gilbert, Simon; Hacker, Alex; Hill, Mike; Holmes, Michael; Iona, Andri; Kerosi, Rene; Lancaster, Garry; Lewington, Sarah; Lin, Kuang; McDonnell, John; Millwood, Iona; Nie, Qunhua; Radhakrishnan, Jayakrishnan; Ryder, Paul; Sansome, Sam; Schmidt, Dan; Sherliker, Paul; Sohoni, Rajani; Stevens, Becky; Turnbull, Iain; Wang, Jenny; Wang, Lin; Wright, Neil; Yang, Xiaoming; Han, Xiao; Hou, Can; Liu, Chao; Xia, Qingmei; Pang, Zengchang; Gao, Ruqin; Li, Shanpeng; Wang, Shaojie; Liu, Yongmei; Du, Ranran; Zang, Yajing; Cheng, Liang; Tian, Xiaocao; Zhang, Hua; Zhai, Yaoming; Ning, Feng; Sun, Xiaohui; Li, Feifei; Lv, Silu; Wang, Junzheng; Hou, Wei; Zou, Mingyuan; Jiang, Ge; Zhou, Xue; Yang, Liqiu; He, Hui; Yu, Bo; Li, Yanjie; Xu, Qinai; Kang, Quan; Guo, Ziyan; Wang, Dan; Hu, Ximin; Chen, Jinyan; Fu, Yan; Fu, Zhenwang; Wang, Xiaohuan; Weng, Min; Guo, Zhendong; Wu, Shukuan; Li, Yilei; Li, Huimei; Fu, Zhifang; Wu, Ming; Zhou, Yonglin; Zhou, Jinyi; Tao, Ran; Yang, Jie; Su, Jian; Liu, Fang; Zhang, Jun; Hu, Yihe; Lu, Yan; Ma, Liangcai; Tang, Aiyu; Zhang, Shuo; Jin, Jianrong; Liu, Jingchao; Tang, Zhenzhu; Chen, Naying; Huang, Ying; Li, Mingqiang; Meng, Jinhuai; Pan, Rong; Jiang, Qilian; Lan, Jian; Liu, Yun; Wei, Liuping; Zhou, Liyuan; Wang, Ningyu Chen Ping; Meng, Fanwen; Qin, Yulu; Wang, Sisi; Wu, Xianping; Zhang, Ningmei; Chen, Xiaofang; Zhou, Weiwei; Luo, Guojin; Li, Jianguo; Zhong, Xunfu; Liu, Jiaqiu; Sun, Qiang; Ge, Pengfei; Ren, Xiaolan; Dong, Caixia; Zhang, Hui; Mao, Enke; Wang, Xiaoping; Wang, Tao; zhang, Xi; Zhang, Ding; Zhou, Gang; Feng, Shixian; Chang, Liang; Fan, Lei; Gao, Yulian; He, Tianyou; Sun, Huarong; He, Pan; Hu, Chen; Zhang, Xukui; Wu, Huifang; Yu, Min; Hu, Ruying; Wang, Hao; Qian, Yijian; Wang, Chunmei; Xie, Kaixu; Chen, Lingli; Zhang, Yidan; Pan, Dongxia; Gu, Qijun; Huang, Yuelong; Chen, Biyun; Yin, Li; Liu, Huilin; Fu, Zhongxi; Xu, Qiaohua; Xu, Xin; Zhang, Hao; Long, Huajun; Li, Xianzhi; Zhang, Libo; Qiu, Zhe
Source
BMC Neurology. September 14, 2023, Vol. 23 Issue 1
Subject
Language
English
ISSN
1471-2377
Abstract
Abstract Background There is uncertainty about the optimum sleep duration for risk of different subtypes of stroke and ischaemic heart disease. Methods The present analyses involved 409,156 adults in the China Kadoorie Biobank study without a prior history of coronary heart disease or stroke or insomnia symptoms. The mean age of study participants was 52 years and 59% were women. Self-reported sleep duration including daytime napping was recorded using a questionnaire. The adjusted hazard ratios (HRs) for disease outcomes associated with sleep duration were estimated by Cox proportional hazards after adjustment for confounding factors. Results The overall mean (SD) sleep duration was 7.4 (1.4) hours. The associations of sleep duration with CVD types were U-shaped, with individuals reporting 7-8 h of sleep having the lowest risks. Compared with those who typically slept 7-8 h, individuals with very short sleep duration ([less than or equal to] 5 h) had adjusted HRs of 1.10 (95% CI 1.04-1.16), 1.07 (1.01-1.13), 1.19 (1.06-1.33) and 1.23 (1.10-1.37) for total stroke, ischaemic stroke (IS), Intracerebral haemorrhage (ICH) and major coronary events (MCE), respectively. Likewise, individuals with very long sleep duration ([greater than or equal to] 10 h) had HRs of 1.12 (1.07-1.17), 1.08 (1.03-1.14), 1.23 (1.12-1.35) and 1.22 (1.10-1.34) for the same diseases, respectively, with little differences by sex and age. The patterns were similar for all-cause mortality. Conclusions While abnormal sleep duration ([less than or equal to] 6 h or [greater than or equal to] 9 h) was associated with higher risks of CVD, the risks were more extreme for those reporting [less than or equal to] 5 or [greater than or equal to] 10 h, respectively and such individuals should be prioritised for more intensive treatment for CVD prevention. Keywords: Sleep duration, Prospective studies, Stroke, Myocardial infarction
Author(s): Yiping Chen[sup.1,2], Christiana Kartsonaki[sup.1,2], Robert Clarke[sup.1,2], Yu Guo[sup.3], Huaidong Du[sup.1,2], Canqing Yu[sup.4,5], Ling Yang[sup.1,2], Pei Pei[sup.5], Rebecca Stevens[sup.2], Sushila Burgess[sup.2], Yujie Hua[sup.6], Junshi Chen[sup.7], Jun Lv[sup.4,5], Liming Li[sup.4,5], Zhengming [...]
Author(s): Yiping Chen[sup.1,2], Christiana Kartsonaki[sup.1,2], Robert Clarke[sup.1,2], Yu Guo[sup.3], Huaidong Du[sup.1,2], Canqing Yu[sup.4,5], Ling Yang[sup.1,2], Pei Pei[sup.5], Rebecca Stevens[sup.2], Sushila Burgess[sup.2], Yujie Hua[sup.6], Junshi Chen[sup.7], Jun Lv[sup.4,5], Liming Li[sup.4,5], Zhengming [...]