학술논문
Epicardial fat thickness is associated to type 2 diabetes mellitus in Korean men: a cross-sectional study
Document Type
Report
Source
Cardiovascular Diabetology. May 3, 2015, Vol. 14
Subject
Language
English
Abstract
Author(s): Hyejin Chun[sup.1] , Eunkyung Suh[sup.2] , A Ri Byun[sup.3] , Hae Ran Park[sup.3] and Kyung Won Shim[sup.3] Background Obesity and insulin resistance are important risk factors of diabetes and [...]
Background Visceral fat, including epicardial fat (EF) is recognized as a responsible factor of cardiovascular disease. The aim of this study was to investigate the relationship between EF and diabetes in Korean men. Methods EF thickness was measured in the left main coronary artery fat tissue (LMCA-fat) by low-dose chest CT scans in 1,048 Korean men (age above 20 years). LMCA-fat values were divided into quartiles and the prevalence of diabetes was analyzed based on the quartiles of LMCA-fat values using logistic regression. Results There were significant correlations between LMCA-fat and body mass index (r = 0.169, p = 0.004), waist circumference (r = 0.172, p < 0.001), fasting glucose (r = 0.106, p = 0.037) and HbA1c (r = 0.176, p < 0.001). The patients in the higher LMCA-fat quartiles were associated with higher prevalence of diabetes (p for trend Conclusion These findings indicate that increased EF thickness is independently associated with the prevalence of diabetes in Korean men. Keywords: Epicardial fat tissue, Diabetes, Low-dose chest CT, Visceral fat
Background Visceral fat, including epicardial fat (EF) is recognized as a responsible factor of cardiovascular disease. The aim of this study was to investigate the relationship between EF and diabetes in Korean men. Methods EF thickness was measured in the left main coronary artery fat tissue (LMCA-fat) by low-dose chest CT scans in 1,048 Korean men (age above 20 years). LMCA-fat values were divided into quartiles and the prevalence of diabetes was analyzed based on the quartiles of LMCA-fat values using logistic regression. Results There were significant correlations between LMCA-fat and body mass index (r = 0.169, p = 0.004), waist circumference (r = 0.172, p < 0.001), fasting glucose (r = 0.106, p = 0.037) and HbA1c (r = 0.176, p < 0.001). The patients in the higher LMCA-fat quartiles were associated with higher prevalence of diabetes (p for trend Conclusion These findings indicate that increased EF thickness is independently associated with the prevalence of diabetes in Korean men. Keywords: Epicardial fat tissue, Diabetes, Low-dose chest CT, Visceral fat