학술논문

The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults
Document Type
Academic Journal
Source
JAMA, The Journal of the American Medical Association. Jan 3, 1996, Vol. v275 Issue n1, p50, 5 p.
Subject
Acute respiratory distress syndrome -- Risk factors
Alcoholism -- Complications
Language
ISSN
0098-7484
Abstract
A history of regular alcohol abuse may increase the risk of acute respiratory distress syndrome (ARDS) in people with critical illnesses. ARDS is the accumulation of fluid in and around the lungs, often causing patients to require artificial respiration. Researchers analyzed alcohol abuse and the outcomes of 351 patients in intensive care units who had significant risk factors for ARDS. These risk factors included blood infection, multiple blood transfusions, trauma to the torso, aspiration of stomach contents, several fractures, and pancreatitis. Among the patients, 34% had a history of alcohol abuse. ARDS occurred in 43% of the patients with a history of alcohol abuse and 22% of the patients without such a history. Among the patients with ARDS, the death rate was 65% for those who had chronically abused alcohol and 36% for those who had not.
Objective.--To determine the effect of a history of chromic alcohol abuse on the incidence of acute respiratory distress syndrome (ARDS) and in-hospital mortality. Design.--Prospective cohort study. Patients.--A total of 351 medical and surgical intensive care unit patients with one of seven at-risk diagnoses for the development of ARDS. Main Outcome Measures.--The development of ARDS and in-hospital mortality. Results.--Of the 351 patients enrolled in the study, the incidence of ARDS in patients with a history of alcohol abuse was significantly higher than in patients without a history of alcohol abuse (43% vs 22%) (P