학술논문
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone
Document Type
Academic Journal
Author
Source
The New England Journal of Medicine. April 8, 1993, Vol. v328 Issue n14, p997, 5 p.
Subject
Language
ISSN
0028-4793
Abstract
Individuals with generalized resistance to thyroid hormone may have a higher risk of developing attention deficit-hyperactivity disorder than other individuals. Generalized resistance to thyroid hormone is characterized by decreased response of peripheral and pituitary gland tissues to thyroid hormone. Among 104 adults and children in whom responsiveness to thyroid hormone was measured, 49 had attention deficit-hyperactivity disorder and 55 did not. Fifty percent of the adults with resistance to thyroid hormone had attention deficit-hyperactivity disorder, compared with only 7% of the adults with normal responsiveness to thyroid hormone. Seventy percent of the children with resistance to thyroid hormone had attention deficit-hyperactivity disorder, compared with only 20% of the children with normal responsiveness to thyroid hormone.