부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ejpn.2006.02.002 Byline: Gustavo Malinger (a), Neriman Zahalka (a), Dvora Kidron (b), Liat Ben-Sira (c), Dorit Lev (d), Tally Lerman-Sagie (e) Abstract: Cerebellar haemorrhage is a rare prenatal event. Possible aetiologies for foetal intracranial haemorrhage include: trauma, asphyxia, infection, vascular defects, blood dyscrasias, ingestion of drugs and alloimmune and isoimmune thrombocytopenia. We report the ultrasonographic diagnosis of a cerebellar haematoma at 21 weeks of gestation. The foetus succumbed at 33 weeks of gestation following rupture of a subcapsular liver haematoma. An autopsy demonstrated a placental foetal thrombotic vasculopathy and thrombi in the chorionic vessels. We assume that hypercoagulability was responsible for the multiple infarcts in the foetus with haemorrhagic transformation in the cerebellum and liver. The differential diagnosis of foetal cerebellar haemorrhage includes maternal hypercoagulability; in this case multiple haemorrhagic/ischaemic events may be encountered during the pregnancy. A thorough investigation to elucidate the aetiology is pertinent in every case of foetal cerebellar haemorrhage in order to enable accurate counselling and correct management. Author Affiliation: (a) Ultrasound Unit, Department of Obstetrics and Gynecology, The Edith Wolfson Medical Centre, Holon, Israel (b) Department of Pathology, Sapir Medical Centre, Kfar-Saba, Israel (c) Paediatric Radiology Unit, Tel-Aviv Medical Centre, Tel-Aviv, Israel (d) Genetics Institute, The Edith Wolfson Medical Centre, Holon, Israel (e) Paediatric Neurology Unit, The Edith Wolfson Medical Centre, P.O. Box 5, 58100 Holon, Israel Article History: Received 19 October 2005; Revised 5 February 2006; Accepted 15 February 2006