학술논문
BDNF A196G and C270T gene polymorphisms and susceptibility to multiple sclerosis in the polish population. Gender differences
Document Type
Report
Author abstract
Author abstract
Author
Source
Journal of Neuroimmunology. Jan, 2008, Vol. 193 Issue 1-2, p170, 3 p.
Subject
Language
English
ISSN
0165-5728
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jneuroim.2007.10.013 Byline: Dagmara Mirowska-Guzel (a)(b), Anna Mach (a), Grazyna Gromadzka (a)(b), Andrzej Czlonkowski (b), Anna Czlonkowska (a)(b) Keywords: Multiple sclerosis; BDNF; Gender differences Abstract: Two single nucleotide polymorphisms of the human BDNF gene, G196A and C270T, and their impact on the susceptibility to MS and disease progression in the Polish population were investigated. Increased risk of the disease was found for 196G/G carriers (OR -- 1.63, p =0.01) (only females) and 270C/T carriers (OR -- 7.76, p Author Affiliation: (a) 2nd Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland (b) Department of Clinical and Experimental Pharmacology, Medical University of Warsaw, Krakowskie Przedmiescie 26/28, 00-297 Warsaw, Poland Article History: Received 19 July 2007; Revised 17 October 2007; Accepted 17 October 2007