학술논문

Ambient Air Pollution and Vision Disorder: A Systematic Review and Meta-Analysis
Document Type
Report
Source
Toxics. March, 2024, Vol. 12 Issue 3
Subject
China
Language
English
ISSN
2305-6304
Abstract
The effects of air pollution on physical health are well recognized, with many studies revealing air pollution’s effects on vision disorder, yet no relationship has been established. Therefore, a meta-analysis was carried out in this study to investigate the connection between vision disorder and ambient particles (diameter ≤ 2.5 µm (PM[sub.2.5] ), diameter ≤ 10 µm (PM[sub.10] )) and gaseous pollutants (nitrogen dioxide (NO[sub.2] ), sulfur dioxide (SO[sub.2] ), carbon monoxide (CO), Ozone (O[sub.3] )). Twelve relevant studies published by 26 February 2024 were identified in three databases. A pooled odds ratios (ORs) of 95% confidence intervals (CIs) were obtained using random-effects meta-analysis models. Meta-analysis results revealed that for every 10 µg/m[sup.3] increase in PM[sub.2.5] and NO[sub.2] exposure, a substantially higher incidence of vision disorder was observed (OR = 1.10; 95% CI: 1.01, 1.19; OR = 1.08, 95% CI: 1.00, 1.16). No significant correlation existed between exposure to PM[sub.10] , SO[sub.2] and CO and vision disorder. However, O[sub.3] exposure was negatively associated with vision disorder. In addition, subgroup analyses revealed that PM[sub.2.5] exposure was significantly correlated with the risk of glaucoma and age-related macular degeneration and that children and adolescents were more susceptible to NO[sub.2] and PM[sub.2.5] than adults. Overall, exposure to air pollutants, especially PM[sub.2.5] and NO[sub.2] , may increase the incidence of vision disorder.
Author(s): Zhuo Han [1,2,†]; Chao Zhao [3,†]; Yuhua Li [4]; Meng Xiao [1,2]; Yuewei Yang [1,2]; Yizhuo Zhao [1,2]; Chunyu Liu [1,2]; Juan Liu (corresponding author) [1,2,*]; Penghui Li (corresponding [...]