부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ecoenv.2005.08.002 Byline: Wu Jifa (a)(b), Zhiming Yu (a), Song Xiuxian (a), Wang You (a) Keywords: Lateolabrax japonicus; Antioxidant system; B[a]P; SDBS; SOD; CAT; GPx; GST; GSH; AChE; iNOS Abstract: Fish Lateolabrax japonicus were exposed to 0.1 and 1mg/L of anion surfactant sodium dodecylbenzene sulfonate (SDBS) and to 2 and 20[mu]g/L of benzo[a]pyrene (B[a]P) for 6, 12, and 18 days, with control and solvent control groups. Liver antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH), and glutathione S-transferase (GST), were determined; brain acetylcholinesterase (AChE) and liver inducible nitric oxide synthase (iNOS) activities were also measured. The results indicated that (1) L. japonicus avoided oxidative damage through antioxidant systems; (2) SOD, GPx, and GSH were induced, and GST was inhibited and then induced by B[a]P exposure; and (3) CAT, GPx, and AChE were induced while iNOS was inhibited, and GST was induced and then inhibited by SDBS stress in experimental period. Author Affiliation: (a) Key Laboratory of Marine Ecology and Environmental Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China (b) Graduate School of the Chinese Academy of Science, Beijing 100039, China Article History: Received 26 December 2004; Revised 30 July 2005; Accepted 15 August 2005