학술논문

Growth of artificially fed infant rats: effects of supplementation with insulin-like growth factor I
Regulatory, Integrative and Comparative Physiology
Document Type
Academic Journal
Source
American Journal of Physiology (Consolidated). May 1997, Vol. 272 Issue 5, pR1532, 8 p.
Subject
Physiological aspects
Somatomedins -- Physiological aspects
Growth (Physiology) -- Physiological aspects
Gastrointestinal system -- Physiological aspects
Insulin-like growth factors -- Physiological aspects
Growth -- Physiological aspects
Language
ISSN
0002-9513
Abstract
The biological effects of milk-borne insulin-like growth factor I (IGF-I) on the infant growth were analyzed in gastronomized suckling rats that were chronically fed with a rat milk substitute (RMS) without growth factors. Rat pups fed with RMS without peptide growth factors and supplemented with IGF-I exhibited enhanced weight gain and normal skeletal growth. Furthermore, IGF-I-fed animals exhibited enhanced enterocyte migration in the gastrointestinal tract tissues.