부산대학교 도서관

Background It was hypothesized that a mobile health (mHealth) intervention would elicit greater improvements in systolic blood pressure and other cardiometabolic risk factors at 12 weeks, which would be better maintained over 52 weeks, compared to the active control intervention. Methods Eligible participants ([greater than or equai to]2 metabolic syndrome risk factors) were randomized to the mHealth intervention (n = 75) or the active control group (n = 74). Blood pressure and other cardiometabolic risk factors were measured at baseline and at 12, 24 and 52 weeks. Both groups received an individualized exercise prescription and the intervention group additionally received a technology kit for home monitoring of biometrics and physical activity. Results Analyses were conducted on 67 participants in the intervention group (aged 56.7 [+ or -] 9.7 years; 71.6% female) and 60 participants in the active control group (aged 59.1 [+ or -] 8.4 years; 76.7% female). At 12 weeks, baseline adjusted mean change in systolic blood pressure (primary outcome) was greater in the active control group compared to the intervention group (-5.68 mmHg; 95% CI -10.86 to -0.50 mmHg; p = 0.03), but there were no differences between groups in mean change for secondary outcomes. Over 52-weeks, the difference in mean change for systolic blood pressure was no longer apparent between groups, but remained significant across the entire population (time: p < 0.001). Conclusions In participants with increased cardiometabolic risk, exercise prescription alone had greater short-term improvements in systolic blood pressure compared to the mHealth intervention, though over 52 weeks, improvements were equal between interventions. Trial registration ClinicalTrials.gov http://NCT01944124 Keywords: Mobile health, Metabolic syndrome, Exercise prescription, Exercise intervention, Disease prevention, Rural health
Author(s): Robert J Petrella[sup.1,2,3] , Melanie I Stuckey[sup.2,3] , Sheree Shapiro[sup.2] and Dawn P Gill[sup.1,2,3,4] Background Cardiovascular diseases are the leading cause of morbidity and mortality world-wide [1] and patients [...]