학술논문
Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene
Document Type
Academic Journal
Author
Source
Proceedings of the National Academy of Sciences of the United States. June 21, 1994, Vol. 91 Issue 13, p5918, 4 p. table
Subject
Language
ISSN
0027-8424
Abstract
An alpha subunit of a GTP binding protein and a corticotropin receptor were localized at the 18th chromosome pericentromeric region, revealing a susceptibility gene with a complex inheritance mode. The chromosome 18 DNA markers were associated with hereditary manic-depressive illness. A nonparametric method, which used a dominant and recessive model, helped study such inherited illness.