학술논문
Nerve growth factor-mediated paracrine regulation of hepatic stellate cells by multipotent mesenchymal stromal cells
Document Type
Academic Journal
Author
Source
Life Sciences. August 12, 2009, Vol. 85 Issue 7-8, p291, 5 p.
Subject
Language
English
ISSN
0024-3205
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.lfs.2009.06.007 Byline: Nan Lin, Kunpeng Hu, Si Chen, Shujie Xie, Zhaofeng Tang, Jizong Lin, Ruiyun Xu Keywords: Multipotent mesenchymal stromal cells; Mesenchymal stem cell; Hepatic stellate cell; Apoptosis; Nerve growth factor; Regulation Abstract: Multipotent mesenchymal stromal cells (MSC) have been reported to prevent the development of liver fibrosis and have emerged as a promising strategy for cell-based therapy. However, the underlying therapeutic mechanism remains unclear. Hepatic stellate cells (SC) activation is a pivotal event in the development of liver fibrosis. Author Affiliation: Department of Hepatobiliary Surgery, 3rd Affiliated Hospital, Sun Yat-Sen University, GuangZhou 510630, PR China Article History: Received 23 March 2009; Accepted 13 June 2009