학술논문
Esophageal motility disorders: new perspectives from high-resolution manometry and histopathology
Review
Review
Document Type
Academic Journal
Author
Source
Journal of Gastroenterology. April 2018, Vol. 53 Issue 4, p484, 10 p.
Subject
Language
English
ISSN
0944-1174
Abstract
Author(s): Hiroki Sato [sup.1], Kazuya Takahashi [sup.1], Ken-ichi Mizuno [sup.1], Satoru Hashimoto [sup.1], Junji Yokoyama [sup.1], Go Hasegawa [sup.2], Shuji Terai [sup.1] Author Affiliations: (1) 0000 0004 0639 8670, grid.412181.f, [...]
High-resolution manometry (HRM) and peroral endoscopic myotomy (POEM) have contributed significantly to the field of esophageal motility disorders in recent years. The development of HRM has categorized various esophageal motility disorders with a focus on a diverse range of manometric anomalies. Additionally, the Chicago classification criteria is widely used for manometric diagnosis. Moreover, POEM was introduced as a minimally invasive radical therapy for achalasia and shows promise for other spastic esophageal motility disorders as well. POEM has also enabled a transluminal endoscopic approach for determining the histology of the esophageal muscle layer, which is expected to assist in elucidating the etiology of disorders associated with esophageal motility. The purpose of this review is to update the diagnosis, pathology, and treatment of esophageal motility disorders, with a focus on the recent advances in this field.
High-resolution manometry (HRM) and peroral endoscopic myotomy (POEM) have contributed significantly to the field of esophageal motility disorders in recent years. The development of HRM has categorized various esophageal motility disorders with a focus on a diverse range of manometric anomalies. Additionally, the Chicago classification criteria is widely used for manometric diagnosis. Moreover, POEM was introduced as a minimally invasive radical therapy for achalasia and shows promise for other spastic esophageal motility disorders as well. POEM has also enabled a transluminal endoscopic approach for determining the histology of the esophageal muscle layer, which is expected to assist in elucidating the etiology of disorders associated with esophageal motility. The purpose of this review is to update the diagnosis, pathology, and treatment of esophageal motility disorders, with a focus on the recent advances in this field.