학술논문

Apolipoprotein E polymorphism and serum lipids in a randomized, prospective trial of an infant diet with reduced saturated fat and cholesterol
Document Type
Academic Journal
Source
Pediatrics. Oct, 1996, Vol. v98 Issue n4, p757, 6 p.
Subject
Low-fat diet -- Health aspects
Infants -- Food and nutrition
Apolipoproteins -- Measurement
Language
ISSN
0031-4005
Abstract
A diet low in saturated fat and cholesterol appears to have a greater effect on circulating fat levels in infants than the genetic presence of a fat metabolizing protein called apolipoprotein E (apoE). ApoE does, however, seem to influence fat levels early in infancy. Blood fat, cholesterol, and apo levels were measured in 1,062 healthy 7-month-old infants before and after six months of either an unrestricted diet or a diet low in fat and cholesterol. The group eating the special diet had similar cholesterol levels at the beginning and end of the study period while cholesterol levels increased in the group eating a routine diet.
ABSTRACT. Background. The inherited apolipoprotein E (apoE) phenotype may determine effectiveness of dietary atherosclerosis prevention. This study analyzes the effects of apoE phenotypes on changes in serum lipid concentrations in [...]