학술논문

Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma
Document Type
Academic Journal
Source
PLoS Medicine. April, 2007, Vol. 4 Issue 4, p702, 13 p.
Subject
United States
Language
English
ISSN
1549-1277
Abstract
ABSTRACT Background The presence of tumor-specific mutations in the cancer genome represents a potential opportunity for pharmacologic intervention to therapeutic benefit. Unfortunately, many classes of oncoproteins (e.g., transcription factors) are [...]