부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.breast.2006.12.008 Byline: Giulia Veronesi (a), Paolo Scanagatta (a), Aron Goldhirsch (b), Mario Rietjens (c), Marco Colleoni (b), Giuseppe Pelosi (d)(e), Lorenzo Spaggiari (a)(e) Keywords: Chest wall surgery; Advanced breast cancer; Patient satisfaction; Palliation Abstract: Between 1998 and 2003 we observed 15 women who underwent full thickness chest wall resection (FTCWR) followed by plastic reconstruction for locally recurrent or primary breast cancer. Preoperative symptoms were: pain (5 patients), malodorous ulceration (3 patients), presence of tumour mass (4 patients) and thoracic deformity (2 patients). One patient was asymptomatic. Surgery was partial sternectomy with rib resection in 9 patients, rib resection alone in 5, and total sternectomy in one. No perioperative mortality or major morbidity occurred; minor complications occurred in 3 patients (20%). Five of the six surviving patients reported a positive overall outcome in a telephonic interview. Median overall and disease-free survival were 23.4 and 17.5 months, respectively. In conclusion, FTCWR is a safe procedure with low morbidity and mortality that can provide good symptoms palliation in patients with locally advanced breast malignancies, so it should be considered more often by interdisciplinary care providers in those patients who fail to respond to classic multimodality treatment. Author Affiliation: (a) Division of Thoracic Surgery, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy (b) Department of Medicine, Division of Medical Oncology, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy (c) Division of Plastic Surgery, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy (d) Division of Pathology, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy (e) School of Medicine, University of Milan, 20100 Milan, Italy Article History: Received 28 July 2006; Revised 21 November 2006; Accepted 11 December 2006