학술논문
Oxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: relationship between kinetics and distribution of alkali-labile lesions
Document Type
Academic Journal
Author
Source
Journal of Physical Chemistry B. Feb 14, 2008, Vol. 112 Issue 6, 1834-1844
Subject
Language
English
ISSN
1520-6106
Abstract
The sequence dependence of the initial one-electron oxidation of guanine is compared by using the bulky aromatic radical cation of the pyrene derivative, 7,8,9,10-tetrahydroxytetrahydrobenzo[a]pyrene (BPT). The oxidation rates and distributions of oxidized guanine end-products are compared with those produced by [C[O.sub.3].sup..-] radicals.