학술논문
Ozone-mediated nitration of phenylalkyl ethers, phenylacetic esters, and related compounds with nitrogen dioxide. The highest Ortho substitution observed in the electrophilic nitration of arenes
Document Type
Academic Journal
Author
Source
Journal of Organic Chemistry. August 23, 1996, Vol. 61 Issue 17, p5944, 4 p.
Subject
Language
ISSN
0022-3263
Abstract
An alternative pathway for the nitration of phenylalkyl ethers, phenylacetic esters and related compounds with nitrogen dioxide is discussed. It produces o-nitro derivatives in high yield and renders high ortho selectivity in the nitration of these compounds as compared to the conventional nitration of these compounds. It results in a higher yield of ortho isomers from the nitration of phenylalkyl ethers than phenylacetic esters, indicating that the pathway favors ortho substitution products.